Vascular Center of Naples

Our Mission Is To Provide Comprehensive, Compassionate and Meaningful Vascular Care to Our Patients.

Minimally-invasive
Outpatient Procedure
Procedure Time
1–2 Hours
Effective Pain Relief
Clinically Proven
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A Breakthrough in Treating Knee Osteoarthritis

Geniculate Artery Embolization

Geniculate Artery Embolization (GAE) is a minimally invasive, image-guided procedure used to treat chronic knee pain caused by osteoarthritis (OA). First described in 2017, GAE works by interrupting the abnormal blood vessel growth (angiogenesis) that contributes to inflammation and pain in the knee joint.

During the procedure, a small catheter is inserted through the skin to access the arteries surrounding the knee. Tiny particles are then delivered to selectively block these geniculate arteries, effectively reducing blood flow to the inflamed areas. This process helps disrupt the cycle of inflammation, relieving pain and improving mobility.

GAE is best suited for patients with mild to moderate osteoarthritis who are not ready or eligible for total knee replacement—or who continue to experience pain despite conservative treatments like physical therapy, medications, or injections. The procedure offers significant pain reduction, minimal downtime, and a faster return to daily activities.

Clinical studies show that GAE can reduce the need for pain medications and knee injections, with cumulative success rates of 85% at 2 years for mild to moderate OA and 70% for severe cases.

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Target the Source of Knee Pain.

How Geniculate Artery Embolization Works

Geniculate Artery Embolization (GAE) is a minimally invasive procedure that targets the small arteries around the knee joint that contribute to pain from osteoarthritis. In osteoarthritic knees, abnormal blood vessel growth—known as angiogenesis—leads to ongoing inflammation and nerve sensitization.

Using image guidance, an interventional radiologist inserts a catheter through a tiny puncture in the skin and navigates it to the geniculate arteries supplying the inflamed areas. Microscopic particles are then released to block these vessels, interrupting the inflammatory process.

By reducing blood flow to the abnormal vasculature, GAE effectively decreases inflammation, relieves pain, and improves function—without the need for general anesthesia or hospitalization. The procedure is performed on an outpatient basis and typically allows patients to return to daily activities within a few days.
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Proven Results

Before & After Photos

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Find Out if You're a Good Candidate.

Is Geniculate Artery Embolization Right for You?

Geniculate Artery Embolization is a promising option for individuals with knee osteoarthritis who
Have been diagnosed with osteoarthritis and suffer from chronic knee pain
Are exploring alternatives to total knee replacement surgery or are not yet ready for surgery
Are not ideal candidates for surgery due to age, obesity, diabetes, or other medical conditions
Have undergone knee replacement but still experience pain and discomfort
Seek long-lasting pain relief and improved knee function
If you're living with knee pain and seeking an alternative to surgery, GAE could be a life-changing option.
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Minimally Invasive. Maximum Relief.

Why Geniculate Artery Embolization is a Treatment Option

Geniculate Artery Embolization (GAE) is an innovative, minimally invasive option for managing knee osteoarthritis pain—especially for patients who aren’t ready for or are not candidates for total knee replacement surgery.

GAE has been shown to significantly reduce knee pain, improve function, and decrease the need for oral pain medications or ongoing injections. Most patients return home the same day, with minimal downtime and a fast recovery timeline. Clinical studies show high success rates: 85% for mild-to-moderate osteoarthritis and 70% for severe cases at two years.

This treatment is especially beneficial for patients who face higher surgical risks due to age, obesity, diabetes, or other chronic health conditions. It is also a valuable option for patients who continue to experience pain after knee replacement surgery.

At the Vascular Center of Naples, we are proud to offer GAE as part of our commitment to providing advanced, evidence-based solutions that help our patients reclaim mobility and quality of life.

Minimal Downtime. Maximum Mobility.

Quick Recovery, Long-Term Relief

Geniculate Artery Embolization (GAE) is performed as a same-day, outpatient procedure—allowing you to return home shortly after treatment with minimal interruption to your daily life.
Most patients resume light activity within 24–48 hours
No general anesthesia, stitches, or large incisions are required
Post-procedure discomfort is typically limited to mild soreness or bruising at the access site
Pain relief and improved function are commonly experienced within 2 to 4 weeks as inflammation subsides
GAE offers a faster, lower-risk recovery than traditional knee surgery, making it a practical and effective option for patients seeking real relief without extended downtime.
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Frequently Asked Questions

What is Geniculate Artery Embolization (GAE)?

GAE is a minimally invasive procedure that blocks specific arteries in the knee to reduce inflammation and pain caused by osteoarthritis. It’s performed by an interventional vascular surgeon using image guidance and a catheter to target and treat the affected arteries.

Who qualifies for GAE?

GAE is ideal for patients with moderate to severe knee osteoarthritis who haven’t found relief with medications, physical therapy, or injections. It’s also a strong option for those looking to delay or avoid knee replacement surgery.

How long does the procedure take?

The GAE procedure typically takes about 1–2 hours. It is performed on an outpatient basis, meaning you can return home the same day with no overnight hospital stay required.

Is GAE painful?

Most patients report only mild discomfort during or after the procedure. A local anesthetic is used, and sedation may be provided to ensure a comfortable experience.

How soon can I resume normal activities?

Light activities can usually be resumed within 24–48 hours. Most patients experience significant pain relief within a few weeks, with continued improvement over time.

Are there risks or side effects?

As with any medical procedure, there are some risks, including minor bruising, temporary inflammation, or rare complications. However, GAE is considered very safe when performed by an experienced interventional radiologist.

Is GAE covered by insurance?

Coverage varies depending on your insurance provider and individual plan. Our team at the Vascular Center of Naples can assist with verifying your benefits and guiding you through the process.

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